URGCP-MRPS24

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, URGCP-MRPS24 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated URGCP-MRPS24 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher URGCP-MRPS24 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated URGCP-MRPS24 expression acts as an unfavorable survival marker.

CESC are the cancer types where URGCP-MRPS24 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSMedianII,III,IV0.0470.830<.00112view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

URGCP-MRPS24–CESC (OS)

Kaplan–Meier survival curve for URGCP-MRPS24 mutant vs wild-type samples in CESC.

Open the CESC breakdown →

Exploration