URB2

Across TCGA patient cohorts, URB2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible URB2-associated genes across cancer lineages are MYBL2, RCAN2, and CDC25A. Each is linked with URB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both URB2-to-partner and partner-to-URB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, URB2 versus MYBL2 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (URB2→partner) and Y-score (partner→URB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYBL2 →	+1.387	+0.266	.001	<.001	3	9
CCRCC	RCAN2 →	-1.316	-0.320	.001	.001	3	9
GBM	CDC25A →	+0.952	+0.293	.001	<.001	3	8
UCEC	UBE2C →	+1.766	+0.269	<.001	<.001	3	8
BRCA	AURKB →	+0.979	+0.223	<.001	<.001	3	8
BRCA	KIF18B →	+1.311	+0.384	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,407 associations by consensus.

URB2 vs MYBL2 — UCEC

Explore this scatter interactively →