URB1

Across TCGA patient cohorts, URB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,533 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible URB1-associated proteins across cancer lineages are TBL3, UTP4, and WDR7. Each is linked with URB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both URB1-to-partner and partner-to-URB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, URB1 versus TBL3 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (URB1→partner) and Y-score (partner→URB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TBL3 →	+0.244	+0.332	<.001	<.001	3	4
PDAC	UTP4 →	+0.265	+0.285	<.001	.001	3	4
CCRCC	WDR7 →	-0.149	-0.474	<.001	<.001	3	4
UCEC	CFAP298 →	+0.509	+0.561	<.001	.001	2	5
LSCC	EVL_S369 →	-0.552	-0.439	<.001	<.001	3	4
LSCC	GART →	+0.310	+0.592	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,533 associations by consensus.

URB1 vs TBL3 — LSCC

Explore this scatter interactively →