URB1

Across TCGA cell cohorts, URB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,263 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible URB1-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, Transcription initiation at RNA polymerase I promoter, and IMP biosynthetic process. Each is linked with URB1 in more than 15 cancer types. Because this analysis shows association rather than direction, both URB1-to-partner and partner-to-URB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by URB1-low versus URB1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (URB1→partner) and Y-score (partner→URB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Nucleolar large rRNA transcription by RNA polymerase I →	+0.120	+0.922	<.001	<.001	3	16
OESOPHAGUS	Transcription initiation at RNA polymerase I promoter →	+0.158	+1.142	.001	.001	3	16
URINARY_TRACT	IMP biosynthetic process →	+0.156	+0.612	.003	.007	3	15
CNS	Transcription by RNA polymerase I →	+0.104	+0.609	<.001	.002	3	15
SKIN	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.102	+0.809	<.001	<.001	3	14
OESOPHAGUS	Maturation of 5.8S rRNA →	+0.114	+1.230	.002	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,263 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by URB1 expression — BLOOD_Lymphoma

Explore this box plot interactively →