Across TCGA patient cohorts, URAD RNA expression is significantly associated with the go_rna of many other GO terms, with 6,521 significant associations in total. STAD shows the largest number of these associations.

The most reproducible URAD-associated GO terms across cancer lineages are Positive regulation of apoptotic signaling pathway, Mitochondrial respiratory chain complex assembly, and Regulation of fatty acid oxidation. Each is linked with URAD in more than 6 cancer types. Because this analysis shows association rather than direction, both URAD-to-partner and partner-to-URAD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (URAD→partner) and Y-score (partner→URAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of apoptotic signaling pathway →	+0.044	+0.373	<.001	<.001	3	7
ESCA	Mitochondrial respiratory chain complex assembly →	+0.065	+0.327	<.001	<.001	3	7
STAD	Regulation of fatty acid oxidation →	+0.050	+0.620	<.001	<.001	3	7
ESCA	Negative regulation of transferase activity →	+0.060	+0.289	<.001	<.001	3	7
STAD	Regulation of carbohydrate metabolic process →	+0.065	+0.485	<.001	<.001	3	7
STAD	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress →	+0.053	+0.417	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,521 associations by consensus.

Exploration

URAD survival (RNA) · tumor vs normal (RNA) · all URAD data types