UQCRC1

Across TCGA pan-cancer cohorts, UQCRC1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated UQCRC1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UQCRC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UQCRC1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and OV show a favorable association.

CCRCC, OV, and HNSC are the cancer types where UQCRC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.583	.016	19	view →
OV	DFS	Median	All	0.942	0.538	.002	16	view →
HNSC	DFS	Tertile	IV	0.860	0.503	.004	15	view →
PDAC	DFS	Median	III,IV	0.166	0.504	.010	12	view →
COAD	DFS	Median	All	1.000	0.926	.026	6	view →
GBM	OS	Median	All	0.896	0.734	.001	5	view →
LSCC	OS	Quartile	II,III,IV	0.948	0.710	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

UQCRC1–CCRCC (DFS)

Open the CCRCC breakdown →