UQCRBP3

Across TCGA pan-cancer cohorts, UQCRBP3 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated UQCRBP3 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher UQCRBP3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated UQCRBP3 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, KIRC, and LUSC are the cancer types where UQCRBP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.669	0.360	.011	66	view →
KIRC	OS	Tertile	II,III,IV	0.723	0.805	.012	63	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	45	view →
ACC	OS	Tertile	All	0.133	0.686	.004	36	view →
UCEC	DFS	Tertile	All	0.680	0.845	.008	36	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
READ	DFS	Tertile	IV	0.179	0.671	<.001	18	view →
BRCA	OS	Tertile	All	0.951	0.917	.045	15	view →
LGG	DFS	Tertile	All	0.650	0.822	.003	14	view →
UCS	DFS	Tertile	III,IV	0.648	0.180	.036	12	view →
THCA	DFS	Tertile	All	0.950	0.803	.019	8	view →
GBM	OS	Median	All	0.294	0.486	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

UQCRBP3–HNSC (OS)

Open the HNSC breakdown →