Across TCGA patient cohorts, UQCR10 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UQCR10-associated genes across cancer lineages are MIR3675, SIGLEC21P, and SPATA31E3P. Each is linked with UQCR10 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCR10-to-partner and partner-to-UQCR10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCR10→partner) and Y-score (partner→UQCR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MIR3675 →	+0.513	+8.531	<.001	<.001	3	2
OV	SIGLEC21P →	+0.030	+5.384	<.001	.005	3	1
OV	SPATA31E3P →	+0.006	+5.572	.002	.004	3	1
OV	MIR8077 →	+0.359	+6.507	<.001	.001	3	1
BLCA	MIR6794 →	+0.522	+7.640	<.001	.009	3	1
UCEC	RPS29P32 →	+0.771	+4.184	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

UQCR10 survival (RNA) · tumor vs normal (RNA) · all UQCR10 data types