UQCC3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UQCC3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible UQCC3-associated genes across cancer lineages are CYP3A54P, MIR5681A, and OPN1MW. Each is linked with UQCC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCC3-to-partner and partner-to-UQCC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCC3→partner) and Y-score (partner→UQCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCACYP3A54P →+0.413+7.640<.001.00931
BLCAMIR5681A →+0.483+7.640<.001.00931
BLCAOPN1MW →+0.039+7.640<.001.00931
BLCAUBE2V1P14 →+0.089+7.640<.001.00931
BLCARNU7-53P →+0.778+7.640<.001.00931
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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