UQCC1

Across TCGA pan-cancer cohorts, UQCC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UQCC1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher UQCC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UQCC1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and GBM are the cancer types where UQCC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.920	.036	24	view →
LSCC	OS	Median	II,III,IV	0.887	0.645	.005	13	view →
GBM	OS	Median	All	0.858	0.772	.009	11	view →
HNSC	DFS	Median	All	0.894	0.981	.009	4	view →
LUAD	OS	Quartile	II,III,IV	0.907	0.543	.015	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UQCC1–COAD (DFS)

Open the COAD breakdown →