UQCC1

Across TCGA patient cohorts, UQCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,902 significant associations in total. COAD shows the largest number of these associations.

The most reproducible UQCC1-associated genes across cancer lineages are NECAB3, AHCY, and GNAI2. Each is linked with UQCC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both UQCC1-to-partner and partner-to-UQCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UQCC1 versus NECAB3 in BRCA, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCC1→partner) and Y-score (partner→UQCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NECAB3 →	+0.926	+0.484	<.001	<.001	3	6
LSCC	AHCY →	+0.694	+0.438	<.001	<.001	3	5
COAD	GNAI2 →	-0.635	-0.442	<.001	.001	3	5
LUAD	GMFG →	-0.587	-0.357	<.001	<.001	3	5
BRCA	MCRIP2 →	+0.816	+0.535	<.001	<.001	3	5
UCEC	CNRIP1 →	-0.716	-0.356	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,902 associations by consensus.

UQCC1 vs NECAB3 — BRCA

Explore this scatter interactively →