UQCC1

Across TCGA patient cohorts, UQCC1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UQCC1-associated genes across cancer lineages are Eosinophils, Neutrophils, and CMP. Each is linked with UQCC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UQCC1-to-partner and partner-to-UQCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by UQCC1-low versus UQCC1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCC1→partner) and Y-score (partner→UQCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Eosinophils →	+0.032	+3.173	.027	.049	3	1
LUSC	Neutrophils →	+0.011	+3.469	.011	.031	3	1
BLCA	CMP →	+0.057	+3.189	.002	.031	3	1
UCEC	CD8+ T-cells →	+0.016	+2.108	.004	.046	3	1
UCEC	CD8+ Tem →	+0.003	+4.481	<.001	.047	3	1
SKCM	Hepatocytes →	-0.020	-2.453	.004	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Eosinophils by UQCC1 expression — LUSC

Explore this box plot interactively →