UQCC1

Across TCGA cell cohorts, UQCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,016 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UQCC1-associated GO terms across cancer lineages are Establishment of protein localization to organelle, Regulation of telomere capping, and Transcription preinitiation complex assembly. Each is linked with UQCC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both UQCC1-to-partner and partner-to-UQCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to organelle grouped by UQCC1-low versus UQCC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UQCC1→partner) and Y-score (partner→UQCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Establishment of protein localization to organelle →	+0.049	+0.721	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of telomere capping →	+0.099	+0.946	<.001	<.001	3	10
BLOOD_Myeloma	Transcription preinitiation complex assembly →	+0.056	+0.625	.002	.005	2	10
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.117	+0.813	.003	.003	3	9
LUNG_NSCLC_LUSC	Negative regulation of telomere capping →	+0.133	+0.917	<.001	<.001	3	9
OESOPHAGUS	Regulation of centriole-centriole cohesion →	+0.153	+0.825	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,016 associations by consensus.

Establishment of protein localization to organelle by UQCC1 expression — PANCREAS

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