UPK3BL1

Across TCGA patient cohorts, UPK3BL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,310 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible UPK3BL1-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Base-excision repair, AP site formation, and High-density lipoprotein particle assembly. Each is linked with UPK3BL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both UPK3BL1-to-partner and partner-to-UPK3BL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by UPK3BL1-low versus UPK3BL1-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK3BL1→partner) and Y-score (partner→UPK3BL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Multi-pass transmembrane protein insertion into ER membrane →	+0.033	+0.510	<.001	<.001	3	5
KIRP	Base-excision repair, AP site formation →	+0.048	+0.606	<.001	<.001	2	6
LGG	High-density lipoprotein particle assembly →	+0.029	+0.380	<.001	.001	3	5
MESO	Transcription-coupled nucleotide-excision repair →	+0.031	+1.124	<.001	<.001	3	4
SCLC	Negative regulation of DNA-templated transcription, elongation →	+0.093	+0.943	<.001	<.001	3	4
ESCA	Planar cell polarity pathway involved in neural tube closure →	+0.092	+0.802	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,310 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by UPK3BL1 expression — LUSC

Explore this box plot interactively →