UPK1A

Across TCGA cell cohorts, UPK1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,634 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible UPK1A-associated GO terms across cancer lineages are Regulation of macroautophagy, Regulation of TORC1 signaling, and Mitotic cytokinesis. Each is linked with UPK1A in more than 7 cancer types. Because this analysis shows association rather than direction, both UPK1A-to-partner and partner-to-UPK1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by UPK1A-low versus UPK1A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UPK1A→partner) and Y-score (partner→UPK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of macroautophagy →	+0.069	+0.371	<.001	.002	3	8
STOMACH	Regulation of TORC1 signaling →	+0.057	+0.724	<.001	.007	3	7
OVARY	Mitotic cytokinesis →	+0.050	+0.485	.001	.002	3	7
LUNG_NSCLC_LUSC	Positive regulation of macroautophagy →	+0.071	+0.373	<.001	.002	3	6
SKIN	Regulation of TOR signaling →	+0.033	+0.378	.002	<.001	3	6
LUNG_NSCLC_LUAD	Zinc ion import into lysosome →	-0.154	-0.557	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,634 associations by consensus.

Regulation of macroautophagy by UPK1A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →