UPF3B

Across TCGA patient cohorts, UPF3B protein abundance is significantly associated with the RNA expression of many other genes, with 15,803 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UPF3B-associated genes across cancer lineages are SUV39H1, FANCB, and VRK1. Each is linked with UPF3B in more than 5 cancer types. Because this analysis shows association rather than direction, both UPF3B-to-partner and partner-to-UPF3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UPF3B versus SUV39H1 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UPF3B→partner) and Y-score (partner→UPF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SUV39H1 →	+0.555	+0.209	<.001	<.001	3	6
UCEC	FANCB →	+0.738	+0.198	.007	.002	3	6
HNSC	VRK1 →	+0.725	+0.159	.002	.003	3	6
BRCA	STMN1 →	+1.125	+0.358	<.001	<.001	3	6
HNSC	DKC1 →	+0.707	+0.222	<.001	<.001	3	6
BRCA	E2F3 →	+0.775	+0.274	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,803 associations by consensus.

UPF3B vs SUV39H1 — LUAD

Explore this scatter interactively →