Q-omics provides the consensus-scored UPF3AP1 profile across patient tissues and cancer cell-line models. UPF3AP1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, UPF3AP1 is differentially expressed in 6, with the highest sampling consensus in THCA. Additionally, UPF3AP1 RNA expression shows 12,289 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight BRCA, THCA, and THYM as cancer lineages where UPF3AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UPF3AP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UPF3AP1 survival associations across molecular data types. UPF3AP1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UPF3AP1 RNA expression–survival associations across cancer types. High UPF3AP1 expression shows unfavorable associations in UVM and OV, but favorable associations in BRCA, CESC, KIRP and GBM. The BRCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for UPF3AP1 RNA expression.
This table summarizes UPF3AP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for UPF3AP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UPF3AP1 shows lower tumor expression in THCA and higher tumor expression in HNSC, STAD, LIHC, READ and COAD. The THCA box plot shows higher UPF3AP1 RNA expression in normal versus tumor tissue (log2 FC = −0.102, t-test p = .002).
This table shows molecular features associated with UPF3AP1 in patient tissues and cancer cell lines. In patient samples, UPF3AP1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
