UOX

Across TCGA patient cohorts, UOX mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UOX-associated genes across cancer lineages are RN7SL147P, MIR3198-1, and RN7SL140P. Each is linked with UOX in more than 1 cancer types. Because this analysis shows association rather than direction, both UOX-to-partner and partner-to-UOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL147P grouped by UOX-low versus UOX-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UOX→partner) and Y-score (partner→UOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL147P →	+0.354	+4.813	<.001	.001	3	1
UCEC	MIR3198-1 →	+0.877	+3.831	.002	.009	3	1
UCEC	RN7SL140P →	+0.199	+4.997	<.001	.003	3	1
UCEC	MIR4452 →	+0.670	+5.292	<.001	.002	3	1
UCEC	RNU6-553P →	+0.732	+4.026	.001	.006	3	1
UCEC	RNU6-39P →	+0.646	+3.661	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RN7SL147P by UOX expression — UCEC

Explore this box plot interactively →