UNKL

Across TCGA patient cohorts, UNKL RNA expression is significantly associated with the protein abundance of many other proteins, with 12,829 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UNKL-associated proteins across cancer lineages are RFX5, RPL5, and ERO1A. Each is linked with UNKL in more than 5 cancer types. Because this analysis shows association rather than direction, both UNKL-to-partner and partner-to-UNKL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNKL versus RFX5 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNKL→partner) and Y-score (partner→UNKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RFX5 →	+0.408	+0.552	<.001	<.001	3	6
GBM	RPL5 →	-0.195	-0.350	.002	.001	3	5
BRCA	ERO1A →	-0.534	-0.517	<.001	.003	3	5
GBM	GTF3C4_S611 →	+0.281	+0.344	.001	.001	2	6
GBM	RPS3A →	-0.171	-0.346	.003	<.001	3	4
HNSC	TXNDC9 →	-0.211	-0.470	.006	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,829 associations by consensus.

UNKL vs RFX5 — HNSC

Explore this scatter interactively →