UNKL

Across TCGA patient cohorts, UNKL protein abundance is significantly associated with the RNA expression of many other genes, with 9,902 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UNKL-associated genes across cancer lineages are FCER1A, ADAMTS9-AS2, and DNAI4. Each is linked with UNKL in more than 4 cancer types. Because this analysis shows association rather than direction, both UNKL-to-partner and partner-to-UNKL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNKL versus FCER1A in CCRCC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNKL→partner) and Y-score (partner→UNKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FCER1A →	+1.186	+0.332	.002	.002	3	5
UCEC	ADAMTS9-AS2 →	+0.915	+0.256	.001	.009	3	5
BRCA	DNAI4 →	+0.587	+0.450	.001	<.001	3	4
BRCA	APBB1 →	+0.987	+0.472	<.001	<.001	3	4
UCEC	MYLK →	+0.854	+0.253	.001	.001	3	4
BRCA	CHRD →	+1.089	+0.358	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,902 associations by consensus.

UNKL vs FCER1A — CCRCC

Explore this scatter interactively →