UNC93B8

Across TCGA patient cohorts, UNC93B8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,781 significant associations in total. THCA shows the largest number of these associations.

The most reproducible UNC93B8-associated GO terms across cancer lineages are Endoplasmic reticulum tubular network formation, Dendritic cell differentiation, and Regulation of proton transport. Each is linked with UNC93B8 in more than 6 cancer types. Because this analysis shows association rather than direction, both UNC93B8-to-partner and partner-to-UNC93B8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum tubular network formation grouped by UNC93B8-low versus UNC93B8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC93B8→partner) and Y-score (partner→UNC93B8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Endoplasmic reticulum tubular network formation →	+0.051	+0.160	<.001	<.001	3	6
ESCA	Dendritic cell differentiation →	+0.046	+0.144	.004	<.001	2	7
STAD	Regulation of proton transport →	+0.038	+0.130	.001	.001	2	7
THYM	Proton motive force-driven ATP synthesis →	+0.023	+0.280	<.001	<.001	3	6
THYM	ATP synthesis coupled electron transport →	+0.023	+0.244	<.001	<.001	3	6
STAD	Negative regulation of innate immune response →	+0.038	+0.107	.001	.002	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,781 associations by consensus.

Endoplasmic reticulum tubular network formation by UNC93B8 expression — STAD

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