UNC93B1

Across TCGA pan-cancer cohorts, UNC93B1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UNC93B1 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UNC93B1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UNC93B1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

LUAD, PDAC, and COAD are the cancer types where UNC93B1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.554	1.000	.003	28	view →
PDAC	DFS	Quartile	All	0.254	0.507	.001	20	view →
COAD	DFS	Quartile	All	0.884	1.000	.040	18	view →
HNSC	DFS	Quartile	All	0.738	0.497	.019	15	view →
CCRCC	DFS	Tertile	III,IV	1.000	0.813	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UNC93B1–LUAD (DFS)

Open the LUAD breakdown →