UNC80

Across TCGA patient cohorts, UNC80 protein abundance is significantly associated with the RNA expression of many other genes, with 1,485 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UNC80-associated genes across cancer lineages are SLC16A8, RASL10A, and NEFH. Each is linked with UNC80 in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC80-to-partner and partner-to-UNC80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC80 versus SLC16A8 in GBM, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC80→partner) and Y-score (partner→UNC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.518	+0.361	.001	.007	3	1
GBM	RASL10A →	+0.954	+0.466	<.001	<.001	3	1
GBM	NEFH →	+0.863	+0.385	<.001	<.001	3	1
GBM	SYNGR1 →	+0.646	+0.360	<.001	<.001	3	1
GBM	PNPLA5 →	+0.320	+0.480	.001	<.001	3	1
GBM	PVALB →	+0.716	+0.351	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,485 associations by consensus.

UNC80 vs SLC16A8 — GBM

Explore this scatter interactively →