UNC80

Across TCGA cell cohorts, UNC80 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,814 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UNC80-associated GO terms across cancer lineages are Internal peptidyl-lysine acetylation, Proton transmembrane transport, and Cytoskeleton-dependent intracellular transport. Each is linked with UNC80 in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC80-to-partner and partner-to-UNC80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Internal peptidyl-lysine acetylation grouped by UNC80-low versus UNC80-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC80→partner) and Y-score (partner→UNC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Internal peptidyl-lysine acetylation →	+0.096	+0.520	<.001	.002	3	6
LUNG_SCLC	Proton transmembrane transport →	+0.105	+1.945	<.001	<.001	3	6
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.081	+2.224	<.001	<.001	3	6
LUNG_NSCLC_LUAD	ATP synthesis coupled electron transport →	+0.075	+0.049	<.001	.002	3	6
LUNG_NSCLC_LUAD	Mitochondrial ATP synthesis coupled electron transport →	+0.075	+0.049	<.001	.002	3	6
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.083	+0.924	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,814 associations by consensus.

Internal peptidyl-lysine acetylation by UNC80 expression — SKIN

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