UNC80

Across TCGA cell cohorts, UNC80 protein abundance is significantly associated with the RNA expression of many other genes, with 203 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible UNC80-associated genes across cancer lineages are PBDC1, HOXB6, and KCNIP3. Each is linked with UNC80 in more than 1 cancer types. Because this analysis shows association rather than direction, both UNC80-to-partner and partner-to-UNC80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC80 versus PBDC1 in BREAST, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC80→partner) and Y-score (partner→UNC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	PBDC1 →	+0.974	+2.402	.004	.003	3	1
BREAST	HOXB6 →	-3.977	-2.401	.002	.003	3	1
BREAST	KCNIP3 →	+2.325	+2.402	.004	.003	3	1
BREAST	HTRA2 →	+0.609	+2.402	.002	.003	3	1
BREAST	TXNDC9 →	+1.353	+2.402	<.001	.003	3	1
BREAST	UAP1 →	+1.973	+2.402	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 203 associations by consensus.

UNC80 vs PBDC1 — BREAST

Explore this scatter interactively →