UNC5A

Across TCGA patient cohorts, UNC5A RNA expression is significantly associated with the protein abundance of many other proteins, with 17,065 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UNC5A-associated proteins across cancer lineages are ARRB1, EPB41L3, and HK3. Each is linked with UNC5A in more than 4 cancer types. Because this analysis shows association rather than direction, both UNC5A-to-partner and partner-to-UNC5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC5A versus ARRB1 in UCEC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC5A→partner) and Y-score (partner→UNC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARRB1 →	+0.443	+0.493	<.001	.003	3	5
GBM	EPB41L3 →	+0.463	+1.046	<.001	<.001	3	5
PDAC	HK3 →	+0.573	+0.476	<.001	<.001	3	5
HNSC	ARRB2 →	+0.303	+0.463	<.001	<.001	3	4
HNSC	CARD16 →	+0.630	+0.604	<.001	.002	3	4
HNSC	CARD9 →	+0.374	+0.523	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,065 associations by consensus.

UNC5A vs ARRB1 — UCEC

Explore this scatter interactively →