UNC45B

Across TCGA patient cohorts, UNC45B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,699 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible UNC45B-associated proteins across cancer lineages are MMRN2, GIMAP7, and GIMAP8. Each is linked with UNC45B in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC45B-to-partner and partner-to-UNC45B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC45B versus MMRN2 in CCRCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC45B→partner) and Y-score (partner→UNC45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MMRN2 →	+0.533	+0.197	<.001	<.001	3	6
BRCA	GIMAP7 →	+0.480	+0.077	<.001	<.001	3	6
GBM	GIMAP8 →	+0.520	+0.054	<.001	<.001	3	6
GBM	IL16 →	+0.587	+0.060	<.001	<.001	3	6
OV	NOSTRIN →	+0.526	+0.061	.001	<.001	3	5
CCRCC	SHANK3 →	+0.394	+0.157	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,699 associations by consensus.

UNC45B vs MMRN2 — CCRCC

Explore this scatter interactively →