UNC13D

Across TCGA patient cohorts, UNC13D protein abundance is significantly associated with the protein abundance of many other proteins, with 33,038 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UNC13D-associated proteins across cancer lineages are UNC13D_S150, VNN2, and WAS. Each is linked with UNC13D in more than 9 cancer types. Because this analysis shows association rather than direction, both UNC13D-to-partner and partner-to-UNC13D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UNC13D versus UNC13D_S150 in UCEC, with a Pearson correlation of 0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC13D→partner) and Y-score (partner→UNC13D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UNC13D_S150 →	+1.221	+0.539	<.001	<.001	3	10
COAD	VNN2 →	+1.127	+0.393	<.001	<.001	3	10
GBM	WAS →	+0.624	+0.441	<.001	<.001	3	10
UCEC	RGS19 →	+0.659	+0.465	<.001	<.001	3	10
BRCA	S100A9 →	+1.533	+0.446	<.001	<.001	3	10
UCEC	SKAP2 →	+0.801	+0.590	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 33,038 associations by consensus.

UNC13D vs UNC13D_S150 — UCEC

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