Across TCGA patient cohorts, UNC13B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,919 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible UNC13B-associated proteins across cancer lineages are DDAH1, UNC13B_S1251, and UNC13B_S254. Each is linked with UNC13B in more than 5 cancer types. Because this analysis shows association rather than direction, both UNC13B-to-partner and partner-to-UNC13B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UNC13B→partner) and Y-score (partner→UNC13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDAH1 →	+0.553	+0.502	<.001	<.001	3	6
BRCA	UNC13B_S1251 →	+1.280	+0.701	.001	<.001	3	5
BRCA	UNC13B_S254 →	+1.257	+0.980	<.001	.003	3	5
BRCA	ARFGEF3 →	+0.425	+0.650	.003	<.001	3	5
BRCA	NOSTRIN →	+0.782	+0.741	<.001	<.001	3	5
BRCA	PKP4 →	+0.526	+0.961	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,919 associations by consensus.

Exploration

UNC13B survival (RNA) · tumor vs normal (RNA) · all UNC13B data types