upstream master lncRNA of the inflammatory chemokine locusGenealiases: []
Q-omics provides the consensus-scored UMLILO profile across patient tissues and cancer cell-line models. UMLILO expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, UMLILO is differentially expressed in 1, with the highest sampling consensus in KIRP. Additionally, UMLILO RNA expression shows 8,038 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LUAD, KIRP, and THYM as cancer lineages where UMLILO shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UMLILO — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UMLILO survival associations across molecular data types. UMLILO RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UMLILO RNA expression–survival associations across cancer types. High UMLILO expression shows unfavorable associations in LUAD, GBM, KIRC, UCEC and ACC, but favorable associations in BRCA. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify LUAD as the clearest survival context for UMLILO RNA expression.
This table summarizes UMLILO tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for UMLILO. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UMLILO shows lower tumor expression in KIRP. The KIRP box plot shows higher UMLILO RNA expression in normal versus tumor tissue (log2 FC = −0.035, t-test p = .021).
This table shows molecular features associated with UMLILO in patient tissues and cancer cell lines. In patient samples, UMLILO shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
