Across TCGA pan-cancer cohorts, UMAD1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated UMAD1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UMAD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated UMAD1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where UMAD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.263	0.906	.002	36	view →
PDAC	DFS	Tertile	All	0.539	0.350	.013	16	view →
CCRCC	DFS	Median	III,IV	0.814	1.000	.028	3	view →
HNSC	DFS	Median	III,IV	0.698	1.000	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: UMAD1 tumor-vs-normal RNA expression · all UMAD1 data types