ULK4

Across TCGA cell cohorts, ULK4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,162 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ULK4-associated GO terms across cancer lineages are Microtubule polymerization, Microtubule organizing center organization, and Mitotic sister chromatid cohesion. Each is linked with ULK4 in more than 9 cancer types. Because this analysis shows association rather than direction, both ULK4-to-partner and partner-to-ULK4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by ULK4-low versus ULK4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK4→partner) and Y-score (partner→ULK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Microtubule polymerization →	+0.093	+0.840	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.092	+0.878	<.001	.007	3	9
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid cohesion →	+0.107	+0.824	<.001	.004	2	10
BREAST	Cellular response to steroid hormone stimulus →	-0.068	-0.681	.009	.004	3	9
URINARY_TRACT	Epidermis development →	-0.112	-0.958	.001	<.001	3	9
SKIN	Regulation of smoothened signaling pathway →	+0.039	+0.690	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,162 associations by consensus.

Microtubule polymerization by ULK4 expression — BLOOD_Leukemia

Explore this box plot interactively →