ULK3

Across TCGA cell cohorts, ULK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,825 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ULK3-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, DNA replication proofreading, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with ULK3 in more than 13 cancer types. Because this analysis shows association rather than direction, both ULK3-to-partner and partner-to-ULK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by ULK3-low versus ULK3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK3→partner) and Y-score (partner→ULK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.128	+0.854	<.001	<.001	3	14
BONE	DNA replication proofreading →	+0.177	+0.996	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.156	+1.157	<.001	<.001	3	14
BLOOD_Leukemia	Copper ion export →	-0.184	-0.788	<.001	<.001	3	13
BONE	Regulation of DNA repair →	+0.070	+0.862	<.001	<.001	3	13
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.114	+1.063	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,825 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by ULK3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →