ULK3

Across TCGA cell cohorts, ULK3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ULK3-associated genes across cancer lineages are MYOD1, SLC15A5, and SCT. Each is linked with ULK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ULK3-to-partner and partner-to-ULK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by ULK3-low versus ULK3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK3→partner) and Y-score (partner→ULK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYOD1 →	+0.018	+4.684	<.001	.002	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	SCT →	+0.241	+4.095	<.001	.009	3	1
BREAST	OR2H1 →	+0.045	+4.228	<.001	.001	3	1
BREAST	OR14J1 →	+0.010	+3.781	<.001	.009	3	1
BREAST	GIMAP1 →	+0.019	+3.415	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MYOD1 by ULK3 expression — LARGE_INTESTINE

Explore this box plot interactively →