ULK2

Across TCGA cell cohorts, ULK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,864 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ULK2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Establishment of protein localization to organelle, and Regulation of organelle assembly. Each is linked with ULK2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ULK2-to-partner and partner-to-ULK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ULK2-low versus ULK2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK2→partner) and Y-score (partner→ULK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.149	+1.176	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.053	+0.862	.001	.008	3	12
LIVER	Regulation of organelle assembly →	+0.036	+2.090	.001	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.127	+1.054	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.151	+1.362	<.001	<.001	3	11
LUNG_SCLC	Vesicle coating →	+0.119	+1.361	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,864 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ULK2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →