ULK1

Across TCGA patient cohorts, ULK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,442 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ULK1-associated proteins across cancer lineages are ZYX_S143, ULK1_S469, and ULK1_S556. Each is linked with ULK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ULK1-to-partner and partner-to-ULK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ULK1 versus ZYX_S143 in GBM, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ULK1→partner) and Y-score (partner→ULK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZYX_S143 →	-0.568	-0.326	<.001	.008	3	4
LSCC	ULK1_S469 →	+0.498	+0.724	.004	.002	3	4
HNSC	ULK1_S556 →	+0.628	+0.718	<.001	<.001	3	4
LSCC	IL16_S845 →	-0.601	-0.398	<.001	.002	3	4
GBM	BRD8 →	+0.229	+0.504	.001	.001	3	4
LSCC	CCDC88B_S597 →	-0.968	-0.736	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,442 associations by consensus.

ULK1 vs ZYX_S143 — GBM

Explore this scatter interactively →