ULBP1

Across TCGA cell cohorts, ULBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,581 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ULBP1-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, Golgi vesicle transport, and L-serine metabolic process. Each is linked with ULBP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ULBP1-to-partner and partner-to-ULBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by ULBP1-low versus ULBP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ULBP1→partner) and Y-score (partner→ULBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to endoplasmic reticulum stress →	+0.097	+1.228	<.001	<.001	3	11
PANCREAS	Golgi vesicle transport →	+0.060	+1.050	.004	.006	3	10
UPPER_AERODIGESTIVE_TRACT	L-serine metabolic process →	+0.146	+0.918	.002	.002	3	10
PANCREAS	L-serine biosynthetic process →	+0.161	+0.843	<.001	<.001	3	10
STOMACH	Positive regulation of response to endoplasmic reticulum stress →	+0.081	+1.627	.005	<.001	3	9
URINARY_TRACT	Endoplasmic reticulum unfolded protein response →	+0.088	+1.134	.009	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,581 associations by consensus.

Response to endoplasmic reticulum stress by ULBP1 expression — OESOPHAGUS

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