UIMC1

Across TCGA pan-cancer cohorts, UIMC1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated UIMC1 data layer compared with 27 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UIMC1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated UIMC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD and UCEC are the cancer types where UIMC1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.288	0.686	.002	21	view →
UCEC	DFS	Median	II,III,IV	1.000	0.438	.016	20	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

UIMC1–LUAD (OS)

Open the LUAD breakdown →