UIMC1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UIMC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,767 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UIMC1-associated proteins across cancer lineages are UIMC1_S677, NPM1, and UIMC1_S653. Each is linked with UIMC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both UIMC1-to-partner and partner-to-UIMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UIMC1 versus UIMC1_S677 in OV, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UIMC1→partner) and Y-score (partner→UIMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVUIMC1_S677 →+0.718+0.318<.001.00237
GBMNPM1 →+0.333+0.291.004.00136
OVUIMC1_S653 →+0.508+0.456.007<.00126
OVABRAXAS1 →+0.382+0.490<.001<.00135
PDACTOP1_S112 →-0.641-0.295<.001<.00135
OVTHOP1 →+0.329+0.490.002.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,767 associations by consensus.

UIMC1 vs UIMC1_S677 — OV

Per-sample scatter of UIMC1 vs UIMC1_S677 in OV (Pearson r = 0.29).

Explore this scatter interactively →

Exploration