UIMC1

Across TCGA cell cohorts, UIMC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,124 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UIMC1-associated GO terms across cancer lineages are Centrosome cycle, Centrosome duplication, and Mitotic chromosome condensation. Each is linked with UIMC1 in more than 14 cancer types. Because this analysis shows association rather than direction, both UIMC1-to-partner and partner-to-UIMC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by UIMC1-low versus UIMC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UIMC1→partner) and Y-score (partner→UIMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Centrosome cycle →	+0.075	+0.990	<.001	<.001	3	15
BONE	Centrosome duplication →	+0.100	+0.496	.007	.003	3	14
PANCREAS	Mitotic chromosome condensation →	+0.182	+0.786	<.001	<.001	3	13
BREAST	Negative regulation of cell cycle phase transition →	+0.068	+0.978	.001	<.001	3	13
BREAST	Positive regulation of rRNA processing →	+0.104	+0.795	.001	.007	3	13
PANCREAS	Microtubule organizing center organization →	+0.069	+0.652	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,124 associations by consensus.

Centrosome cycle by UIMC1 expression — BREAST

Explore this box plot interactively →