UICLM

Across TCGA patient cohorts, UICLM RNA expression is significantly associated with the go_rna of many other GO terms, with 7,081 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible UICLM-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Protein methylation, and Peptidyl-lysine methylation. Each is linked with UICLM in more than 15 cancer types. Because this analysis shows association rather than direction, both UICLM-to-partner and partner-to-UICLM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA processing grouped by UICLM-low versus UICLM-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UICLM→partner) and Y-score (partner→UICLM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Negative regulation of mRNA processing →	+0.054	+0.360	<.001	<.001	3	15
KIRC	Protein methylation →	+0.041	+0.448	<.001	<.001	3	15
KIRC	Peptidyl-lysine methylation →	+0.035	+0.430	<.001	<.001	3	15
KIRC	Peptidyl-lysine modification →	+0.039	+0.455	<.001	<.001	3	15
KIRC	Positive regulation of DNA repair →	+0.034	+0.399	<.001	<.001	3	15
ESCA	Intracellular sphingolipid homeostasis →	+0.071	+0.372	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,081 associations by consensus.

Negative regulation of mRNA processing by UICLM expression — KIRC

Explore this box plot interactively →