UHRF2P1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, UHRF2P1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated UHRF2P1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher UHRF2P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UHRF2P1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LAML show a favorable association.

DLBC, SKCM, and ACC are the cancer types where UHRF2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCDFSTertileAll0.5040.884<.00160view →
SKCMOSMedianII,III,IV0.8250.688<.00146view →
ACCDFSTertileII,III,IV0.3880.695.00624view →
LAMLDFSTertileAll0.6770.421.00524view →
THCADFSMedianIII,IV0.6280.846.02320view →
COADDFSTertileIII,IV0.3820.741.00320view →
MESODFSTertileIV0.1500.402.03615view →
GBMDFSQuartileAll0.5190.196.00212view →
PAADDFSQuartileAll0.3490.511.0329view →
READOSMedianAll0.5410.903.0308view →
UVMOSTertileIII,IV0.2920.653.0486view →
CHOLDFSTertileIII,IV0.1330.779.0386view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

Exploration