UGT3A2

Across TCGA patient cohorts, UGT3A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,050 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible UGT3A2-associated GO terms across cancer lineages are Protein-DNA complex assembly, Positive regulation of cell cycle phase transition, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with UGT3A2 in more than 17 cancer types. Because this analysis shows association rather than direction, both UGT3A2-to-partner and partner-to-UGT3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex assembly grouped by UGT3A2-low versus UGT3A2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT3A2→partner) and Y-score (partner→UGT3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein-DNA complex assembly →	+0.049	+0.602	.002	<.001	3	18
ESCA	Positive regulation of cell cycle phase transition →	+0.042	+0.473	<.001	<.001	3	17
ESCA	Positive regulation of telomerase RNA localization to Cajal body →	+0.054	+0.681	.002	<.001	3	17
ESCA	mRNA export from nucleus →	+0.049	+0.479	<.001	<.001	3	17
THYM	Sister chromatid cohesion →	+0.094	+2.811	<.001	<.001	3	17
ESCA	Mitotic cytokinesis →	+0.077	+0.912	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,050 associations by consensus.

Protein-DNA complex assembly by UGT3A2 expression — ESCA

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