UGT3A2

Across TCGA cell cohorts, UGT3A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,649 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UGT3A2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Positive regulation of dendrite extension, and Aerobic respiration. Each is linked with UGT3A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both UGT3A2-to-partner and partner-to-UGT3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by UGT3A2-low versus UGT3A2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT3A2→partner) and Y-score (partner→UGT3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of myoblast fusion →	+0.091	+0.308	<.001	.003	3	8
PANCREAS	Positive regulation of dendrite extension →	-0.109	-0.194	<.001	.001	3	8
OVARY	Aerobic respiration →	+0.067	+0.839	.009	.006	1	9
BONE	Purine nucleoside triphosphate biosynthetic process →	+0.089	+4.183	.007	.006	2	8
BONE	Purine ribonucleoside triphosphate biosynthetic process →	+0.089	+4.183	.007	.006	2	8
OVARY	Intrinsic apoptotic signaling pathway →	+0.044	+0.774	.009	.008	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Regulation of myoblast fusion by UGT3A2 expression — SKIN

Explore this box plot interactively →