UGT3A2

Across TCGA cell cohorts, UGT3A2 mutation is significantly associated with the mutation status of many other genes, with 1,690 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UGT3A2-associated genes across cancer lineages are DDX60L, ZNF43, and NPAS4. Each is linked with UGT3A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both UGT3A2-to-partner and partner-to-UGT3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX60L grouped by UGT3A2-low versus UGT3A2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT3A2→partner) and Y-score (partner→UGT3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DDX60L →	+4.415	+4.977	.007	.007	1	5
LUNG_SCLC	ZNF43 →	+4.022	+3.722	.003	.003	1	4
LARGE_INTESTINE	NPAS4 →	+2.321	+2.146	.008	.008	1	4
LUNG_NSCLC_LUAD	CEP97 →	+5.000	+4.187	.008	.008	1	4
LARGE_INTESTINE	COL4A4 →	+2.321	+2.536	.001	.001	1	4
CNS	BMPER →	+3.786	+3.055	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,690 associations by consensus.

DDX60L by UGT3A2 expression — OVARY

Explore this box plot interactively →