UGT3A1

Across TCGA patient cohorts, UGT3A1 protein abundance is significantly associated with the RNA expression of many other genes, with 472 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UGT3A1-associated genes across cancer lineages are KCNK10, NKAIN4, and JADE3. Each is linked with UGT3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT3A1-to-partner and partner-to-UGT3A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UGT3A1 versus KCNK10 in CCRCC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT3A1→partner) and Y-score (partner→UGT3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KCNK10 →	+0.310	+0.546	.001	.001	3	1
CCRCC	NKAIN4 →	+2.220	+0.860	<.001	<.001	3	1
CCRCC	JADE3 →	-0.306	-0.568	.009	.004	3	1
CCRCC	TOX3 →	+0.820	+0.784	<.001	<.001	3	1
CCRCC	BBC3 →	-0.360	-0.450	.002	.003	3	1
CCRCC	ETV2 →	-0.195	-0.632	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

UGT3A1 vs KCNK10 — CCRCC

Explore this scatter interactively →