UGT3A1

Across TCGA cell cohorts, UGT3A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 811 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UGT3A1-associated GO terms across cancer lineages are Nucleobase-containing compound transport, NK T cell differentiation, and Negative regulation of tumor necrosis factor superfamily cytokine production. Each is linked with UGT3A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UGT3A1-to-partner and partner-to-UGT3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleobase-containing compound transport grouped by UGT3A1-low versus UGT3A1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT3A1→partner) and Y-score (partner→UGT3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Nucleobase-containing compound transport →	+0.024	+0.042	.003	.003	3	3
SOFT_TISSUE	NK T cell differentiation →	-0.203	-1.082	<.001	.006	3	3
BLOOD_Leukemia	Negative regulation of tumor necrosis factor superfamily cytokine production →	-0.040	-0.040	.004	.009	3	3
BLOOD_Leukemia	Negative regulation of tumor necrosis factor production →	-0.043	-0.040	.002	.009	3	3
BLOOD_Leukemia	Nuclear export →	+0.041	+0.039	.002	.005	2	4
BONE	Epithelial tube branching involved in lung morphogenesis →	-1.493	-0.088	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 811 associations by consensus.

Nucleobase-containing compound transport by UGT3A1 expression — BLOOD_Leukemia

Explore this box plot interactively →