UGT2B7

Across TCGA cell cohorts, UGT2B7 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UGT2B7-associated genes across cancer lineages are CCDC172, IAPP, and NOX5. Each is linked with UGT2B7 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B7-to-partner and partner-to-UGT2B7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by UGT2B7-low versus UGT2B7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B7→partner) and Y-score (partner→UGT2B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCDC172 →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IAPP →	+0.528	+3.906	<.001	.005	3	1
BLOOD_Leukemia	NOX5 →	+0.078	+3.358	<.001	.009	3	1
BLOOD_Lymphoma	CALHM4 →	+0.375	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP1-1 →	+0.069	+5.794	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CCDC172 by UGT2B7 expression — SKIN

Explore this box plot interactively →