UGT2B28

Across TCGA patient cohorts, UGT2B28 mutation is significantly associated with the RNA expression of many other genes, with 2,683 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B28-associated genes across cancer lineages are POC1A, MYO19, and DCPS. Each is linked with UGT2B28 in more than 3 cancer types. Because this analysis shows association rather than direction, both UGT2B28-to-partner and partner-to-UGT2B28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POC1A grouped by UGT2B28-low versus UGT2B28-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B28→partner) and Y-score (partner→UGT2B28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POC1A →	+0.532	+2.716	.007	.003	3	4
UCEC	MYO19 →	+0.510	+2.526	<.001	.001	3	3
UCEC	DCPS →	+0.418	+1.776	.007	.008	3	3
LUAD	FOXM1 →	+1.092	+3.471	.001	.002	3	3
LUAD	DDX55 →	+0.416	+3.485	.004	.002	3	3
SKCM	EXOSC9 →	+0.408	+2.025	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,683 associations by consensus.

POC1A by UGT2B28 expression — UCEC

Explore this box plot interactively →