UGT2B28

Across TCGA cell cohorts, UGT2B28 RNA expression is significantly associated with the go_rna of many other GO terms, with 440 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UGT2B28-associated GO terms across cancer lineages are Positive regulation of antifungal innate immune response, Regulation of TORC2 signaling, and Late endosome to vacuole transport via multivesicular body sorting pathway. Each is linked with UGT2B28 in more than 2 cancer types. Because this analysis shows association rather than direction, both UGT2B28-to-partner and partner-to-UGT2B28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of antifungal innate immune response grouped by UGT2B28-low versus UGT2B28-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B28→partner) and Y-score (partner→UGT2B28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of antifungal innate immune response →	+0.678	+0.083	.004	.007	3	3
BLOOD_Leukemia	Regulation of TORC2 signaling →	+0.066	+0.258	<.001	.005	3	3
BLOOD_Leukemia	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.054	+0.323	.002	.003	3	3
UPPER_AERODIGESTIVE_TRACT	Neurotrophin signaling pathway →	+0.075	+0.027	.004	.009	3	3
BLOOD_Leukemia	Late endosome to vacuole transport →	+0.040	+0.198	.003	.002	3	3
LUNG_SCLC	Regulation of plasma membrane repair →	-0.275	-0.173	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 440 associations by consensus.

Positive regulation of antifungal innate immune response by UGT2B28 expression — BREAST

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